The talented 26 year-old took the fight to the former interim WBA flyweight belt holder from the off to see out a 118-110 and 117-111 (twice) victory over the Panamanian challenger.
Cuadras can now boast a 32-0-1 record since making his debut back in 2008, whilst Concepcion, 29, drops a fourth loss in 36 contests and will need another rebuilding job.
In chief support, Filipino southpaw Jonathan Taconing remains on track for a crack at the world flyweight title after stopping Ramon Garcia Hirales with just seconds to spare. Taconing, 28, ended the scheduled ten round contest with 2:53 on the clock to seal a 21st career triumph and an 18th inside the distance.
Earlier, featherweight Romulo Koasicha out-pointed Edgar Monarrez, whilst Enrique Angeles Jr could only manage a draw with the unheralded Luis Felipe Guiza. Juan Jose Martinez improved to 19-2 with a unanimous win over six rounds against Brian Flores, whilst Santiago Estrada v Daniel Olea ended in stalemate.
Eduardo Hernandez, Valentin Martinez and Luis Hernandez, on his debut, also had their hands raised at the Unidad Deportiva Martín Alarcón.