Khan, 28, has long been linked to a challenge against pound for pound king Mayweather since announcing his intentions to move up to 147lbs in 2012, although missed out on a lucrative pay-per-view bout in 2013 to Marcos Maidana.
Having spent years training with Freddie Roach in LA, Khan was coached alongside Pacquiao for the majority of his success at light-welterweight, giving a potential fight between the two a massive selling point if they did decide to share the ring.
“I’d have to say Floyd (appeals more than Pacquiao). Manny is a great fighter but I want to fight the best,” Khan exclusively told World Boxing News.
“Manny has been beaten five times and Floyd has never been beaten, so I want to be the first person to put a loss on to Floyd Mayweather’s professional boxing record.
“If for some reason a fight between me and Floyd doesn’t materialise, then Manny would be a fantastic opponent. He’s won world titles in six different weight divisions which is an incredible feat. We had some great sparring sessions when Freddie Roach used to train me but in an ideal world, I’d fight Floyd ahead Manny.
“Many people have said that they believe I can beat Mayweather and I would just love the opportunity to show what I can do and show that I can compete with the very best.
“I certainly hope that a victory opens doors for me in 2015 but firstly, I need to concentrate on beating Alexander. He has beaten some great boxers like Andriy Kotelnik, Lucas Matthysse and Marcos Maidana, who caused Mayweather massive problems.”
Right now though, as Khan heads towards the biggest contest of his career in his Las Vegas debut, Alexander is undoubtedly the Bolton man’s sole focus as the media around him predict that a chance to swap punches with the best fighter in the world hangs in the balance.
Amir Khan vs Devon Alexander is live on Sky Sports 1 in the UK on Saturday December 13th in to Sunday 14th at 2am. US viewers can see the fight on Showtime at 10pm ET/PT