The St Helens man has too much in his locker for Spera and can now look forward to a high-profile co-feature slot on the Anthony Joshua v Dominic Breazeale next month.
Marcus Morrison did similar to Murray in claiming the vacant WBC International Silver middleweight strap with a crushing knockout of Jefferson Luiz De Sousa.
Shayne Singleton dropped Adil Anwar twice on his was to an eight round triumph, whilst Warren Baister made it to 4-0 by halting Stanislav Eschner in the opening stanza.
Earlier, Paul Smith Jnr opened the bill and made a successful return from almost a year out by stopping Bronislav Kubin in three rounds. Smith, 33, dropped Kubin twice in the second before finishing the fight in the next session to improve to 36-6.
Lightweight Jono Carroll pushed his own C.V to 10-0 with a six round points win over Jordan Ellison, whilst Callum Johnson proved too hot for Richard Horton to handle, scoring three knockdowns on his way to a first round triumph.
Also on the bill, Tommy Coyle laboured to a six round points win over Reynaldo Mora following a return from injury prior to Sean Mulligan and Ben Sheedy extending their unbeaten runs.
Mulligan won via unanimous decision over four rounds, whilst Sheedy recorded a second round stoppage.