The two-weight world champion lost out on a lucrative rematch with WBC middleweight champion Gennady Golovkin on May 5 after testing positive for Clenbuterol on two occasions.
Canelo has the full backing of the WBC and was reinstated to the list as promised by President Mauricio Sulaiman.
There are real hopes a rematch with Golovkin could happen again in September, with Gary ‘Spike’ O’Sullivan ready to face the winner in December.
Talks ended recently due to an argument over the deal split, although Golovkin has now come down from his 50-50 demands in order to reignite the negotiations.
September 15 is earmarked as the date for round two, just over a month after Canelo’s suspension with the NSAC expires.
Alvarez stands at number one in the rankings as mandatory Jermall Charlo is now the interim title holder.
Charlo will be ordered to face Golovkin should a Canelo deal fall flat again, which is not expected to happen this time around.
Special dispensation was given in order to allow Golovkin and Canelo to finish their feud after a controversial draw last September.
Daniel Jacobs sits at two ahead of a possible IBF title shot, with Demetrius Andrade third, Jason Quigley fourth and Kamil Szeremeta of Poland making up the top five.
WBC Top 20 middleweights (June 2018):
1 Saul Alvarez (Mexico)
2 Daniel Jacobs (US)
3 Demetrius Andrade (US)
4 Jason Quigley (Ireland/US) NABF
5 Kamil Szeremeta (Poland) EBU
6 Roberto Garcia (Mexico-US) SILVER
7 Willie Monroe Jr. (US)
8 Gary O’Sullivan (Ireland)
9 Jack Culcay (Germany)
10 Yamaguchi Falcao (Brazil) LATINO
11 Luis Arias (US)
12 Hugo Centeno, Jr. (US)
13 Immanuwel Aleem (US)
14 Ievgen Khytrov (Ukraine)
15 Esquivia Falcao (Brazil) * CBP/P
16 Tureano Johnson (US)
17 Rob Brant (US)
18 Steve Rolls (Canada)
19 Ruben Diaz (Spain)
20 Yasuyuki Akiyama (Japan) OPBF