The Manny Pacquiao was blowing hot and cold at times, but still had enough in his locker to out-scrap the British-based Irishman in a contest littered with head clashes.
Both boxers suffered cuts in the mid-rounds and it was Horn who coped the better to eventually wear down the dogged challenger.
Corcoran was left struggling to see out of his left eye late on and referee Benjy Esteves Jr. had seen enough in the mid-part of the eleventh.
Horn moves on to a potential clash with mandatory contender and pound for pound star Terence Crawford in April, which promoter Bob Arum says could take place in Las Vegas.
On the undercard, former heavyweight world title challenger Alex Leapai was raging when his contest with Roger Izonritei was halted in the third round and judged to be a technical draw.
Leapai, who lost out to Wladimir Klitschko in his one and only world championship bout, was thoroughly on top for the first two and a half rounds before the out-classed Izonritel was halted on a cut.
Instead of handing Leapai a stoppage win, the bout was ruled a TD to potentially reverse the veteran’s comeback attempts and future title ambitions.
Also on the bill, welterweight Leonardo Zappavigna moved to 37-3 with a third round victory over Nestor Faccio, whilst undefeated super featherweight Paul Fleming also took Vergil Puton out in the third.