The super-lightweight, who had previously won all three of his pro contests, only won two of four rounds of referee Lee Every’s official scorecard.
Wilson, 28, will now have to go back to the drawing board as the interest surrounding his career, stemming from his famous father and brother Chris Jr., intensifies following the weekend’s result.
In other bouts on the bill, British welterweight champion Bradley Skeete scored a unanimous decision over John Thain 16-3 to make a successful first defence of his Lonsdale Belt.
The 29 year-old pushed his record to 25-1 and can boast seven wins on the spin since losing to rival almost Frankie Gavin two years ago to the day.
At middleweight, Lee Markham out-pointed Andrew Robinson over twelve, whilst Boy Jones earned a ten-round points victory over Martin Hillman.
Big-hitting light heavyweight prospect Anthony Yarde continued his fine form with a first round knockout of Ferenc Albert to make it ten wins on the spin.
In other action, Indian star Sanjeev Sahota had too much skill for Gyula Tallosi to remain undefeated in the paid ranks, whilst Johnny Coyle carded a six-round win.