World Boxing News will be scoring live on site tonight as Miguel Cotto and Canelo Alvarez wage war in a 155 pound blockbuster battle.
Puerto Rico v Mexico in itself needs no introduction as the rivalry speaks volumes and should lead to a Fight of the Year contender between two top names in the boxing world.
Cotto, 35, is already a four-weight world champion, whilst Canelo could become a two division ruler should he overcome the veteran at the Mandalay Bay.
In Germany, Arthur Abraham makes yet another defence of his WBO super middleweight title against an Englishman as perennial challenger Martin Murray steps up to the plate.
Abraham has already shared the ring with Carl Froch, Paul Smith and Wayne Elcock with plenty of success in the past and hopes to secure a 44th career win against the St Helens man.
Murray has a fourth chance to finally land that world belt which has eluded him following a draw with Felix Sturm and spirited losses to Sergio Martinez and Gennady Golovkin.
In another world title clash, this time on British soil in Manchester, WBA lightweight champion Darleys Perez fights Anthony Crolla for the second time in four months.
The pair shared twelve rounds at the same venue back in July in a contest that seemed to be edged by the challenger but eventually was carded a draw.
Log on to the WBN website from 4pm ET / 9pm UK to follow how the fights are scored live.