The 32 year-old faces Spada as a huge battle with unified world champion Gennady Golovkin looms large on the horizon and at just under 160lbs seems primed to set-up his third world title chance.
Murray has previously missed out on claiming the WBA and WBC versions against Felix Sturm and Sergio Martinez respectively, when on both occasions there could have been a case made for victory.
Talks for another crack at the WBA, along with Golovkin’s IBO belt have already taken place as revealed to WBN by Murray’s manager Andrew Mikhail this week – for what would be another trip to Monaco for the St Helens man in February.
Opponent Spada, 34, came in at around the same mark just shy of the middleweight limit and goes into the contest as a massive underdog to pull off the upset.
Murray v Spada goes out live on ESPN3 in the US and Channel 5 in the UK on Saturday night.