The 30 year-old, who last fought in 2016, shook off the ring rust to out-point Luis Granados over six rounds.
Jones had previously scored three knockouts in a row after turning pro in 2013 either side of another long absence.
Spending just ten minutes in the ring prior to Friday’s bout, Jones was handed much-needed rounds by Granados as he won 59-55 on all three scorecards.
The victory represented Jones’ third fight on the spin on Mexican soil having previously fought twice in Tijuana in 2016.
Hitting Facebook LIVE to celebrate his triumph, Jones was clearly delighted to be back in action following another period of inactivity.
With time ticking on his stop-start career, Jones is expected to concentrate on being more active to see if his Mayweather genes can prove a success.
By the time older brother Floyd Jr. was the same age, he was already the top star on the planet having defeated Oscar De La Hoya in 2007.
Now 41, Floyd Jr. is considering moving over to UFC in a bid to extend his own combat stint.
